{"id":118420,"date":"2022-09-28T14:04:55","date_gmt":"2022-09-28T14:04:55","guid":{"rendered":"https:\/\/www.proceadecrc03study.com\/the-proceade-study\/"},"modified":"2026-01-14T16:26:44","modified_gmt":"2026-01-14T16:26:44","slug":"the-proceade-study","status":"publish","type":"page","link":"https:\/\/www.proceadecrc03study.com\/en-au\/","title":{"rendered":"The PROCEADE Study"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;100&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;0&#8243; top_padding=&#8221;2&#8243; bottom_padding=&#8221;2&#8243; overlay_alpha=&#8221;50&#8243; equal_height=&#8221;yes&#8221; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; enable_top_divider=&#8221;default&#8221; top_divider=&#8221;gradient&#8221; shape_top_h_use_pixel=&#8221;&#8221; shape_top_height=&#8221;500&#8243; shape_top_color=&#8221;color-138253&#8243; shape_top_opacity=&#8221;70&#8243; shape_top_index=&#8221;0&#8243; enable_bottom_divider=&#8221;default&#8221; bottom_divider=&#8221;gradient&#8221; shape_bottom_h_use_pixel=&#8221;&#8221; shape_bottom_height=&#8221;500&#8243; shape_bottom_color=&#8221;color-138253&#8243; shape_bottom_opacity=&#8221;70&#8243; shape_bottom_index=&#8221;0&#8243; inverted_device_order=&#8221;yes&#8221; auto_height_device=&#8221;yes&#8221; content_parallax=&#8221;0&#8243; uncode_shortcode_id=&#8221;207280&#8243; shape_top_color_type=&#8221;uncode-palette&#8221; shape_bottom_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_percent=&#8221;100&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; override_padding=&#8221;yes&#8221; column_padding=&#8221;4&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; css_animation=&#8221;alpha-anim&#8221; animation_speed=&#8221;600&#8243; parallax_intensity=&#8221;2&#8243; parallax_centered=&#8221;yes&#8221; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;205474&#8243;][vc_custom_heading text_color=&#8221;color-210981&#8243; heading_semantic=&#8221;h1&#8243; text_size=&#8221;h1&#8243; text_weight=&#8221;900&#8243; text_height=&#8221;fontheight-541499&#8243; sub_lead=&#8221;yes&#8221; uncode_shortcode_id=&#8221;477573&#8243; text_color_type=&#8221;uncode-palette&#8221;]The PROCEADE CRC-03 Study[\/vc_custom_heading][vc_column_text text_lead=&#8221;yes&#8221; uncode_shortcode_id=&#8221;152148&#8243;]Evaluating an investigational medicine for metastatic colorectal cancer[\/vc_column_text][vc_row_inner limit_content=&#8221;&#8221;][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;870296&#8243;][vc_button button_color=&#8221;accent&#8221; border_width=&#8221;0&#8243; display=&#8221;inline&#8221; scale_mobile=&#8221;no&#8221; link=&#8221;url:%23study-description|&#8221; uncode_shortcode_id=&#8221;103997&#8243; button_color_type=&#8221;uncode-palette&#8221; width=&#8221;216&#8243;]Learn more[\/vc_button][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column column_width_percent=&#8221;100&#8243; position_horizontal=&#8221;right&#8221; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;982899&#8243; el_id=&#8221;home-hero&#8221; el_class=&#8221;home-hero&#8221;][vc_single_image media=&#8221;118390&#8243; media_width_percent=&#8221;100&#8243; media_ratio=&#8221;one-one&#8221; alignment=&#8221;right&#8221; uncode_shortcode_id=&#8221;386737&#8243; el_id=&#8221;hero-image&#8221; el_class=&#8221;hero-image&#8221;][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;5&#8243; bottom_padding=&#8221;5&#8243; back_color=&#8221;color-190907&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; enable_top_divider=&#8221;default&#8221; top_divider=&#8221;step&#8221; shape_top_h_use_pixel=&#8221;&#8221; shape_top_height=&#8221;60&#8243; shape_top_color=&#8221;color-138253&#8243; shape_top_opacity=&#8221;100&#8243; shape_top_index=&#8221;0&#8243; enable_bottom_divider=&#8221;default&#8221; bottom_divider=&#8221;step&#8221; shape_bottom_h_use_pixel=&#8221;&#8221; shape_bottom_height=&#8221;60&#8243; shape_bottom_color=&#8221;color-210981&#8243; shape_bottom_opacity=&#8221;100&#8243; shape_bottom_index=&#8221;0&#8243; content_parallax=&#8221;0&#8243; uncode_shortcode_id=&#8221;275432&#8243; row_name=&#8221;study-description&#8221; back_color_type=&#8221;uncode-palette&#8221; shape_top_color_type=&#8221;uncode-palette&#8221; shape_bottom_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_percent=&#8221;100&#8243; position_vertical=&#8221;middle&#8221; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; align_medium=&#8221;align_left_tablet&#8221; medium_width=&#8221;0&#8243; align_mobile=&#8221;align_left_mobile&#8221; mobile_width=&#8221;0&#8243; parallax_intensity=&#8221;2&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;107736&#8243;][vc_empty_space empty_h=&#8221;3&#8243;][vc_custom_heading text_weight=&#8221;500&#8243; css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;873399&#8243;]What is the PROCEADE CRC-03 Study?[\/vc_custom_heading][vc_column_text text_color=&#8221;color-jevc&#8221; css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;190436&#8243; text_color_type=&#8221;uncode-palette&#8221;]The PROCEADE CRC-03 Study is a Phase 3 clinical study of an investigational medicine for adults with previously treated metastatic colorectal cancer.<br \/>In Phase 3, the goal is to confirm earlier findings of safety and efficacy in a larger group of people so doctors and regulators can understand the investigational medicine more clearly.[\/vc_column_text][vc_empty_space empty_h=&#8221;3&#8243;][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;7&#8243; bottom_padding=&#8221;7&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;203669&#8243; row_name=&#8221;participate-who&#8221;][vc_column column_width_percent=&#8221;95&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;728112&#8243;][vc_single_image media=&#8221;118396&#8243; media_width_percent=&#8221;100&#8243; media_ratio=&#8221;one-one&#8221; uncode_shortcode_id=&#8221;105079&#8243;][\/vc_column][vc_column column_width_percent=&#8221;95&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; parallax_intensity=&#8221;2&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;196010&#8243;][vc_custom_heading text_weight=&#8221;500&#8243; css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;210804&#8243;]Who can participate?[\/vc_custom_heading][vc_column_text css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;185882&#8243;]The study is enrolling adults with metastatic colorectal cancer that has been previously treated. To be eligible, you must meet these and other requirements which the study doctor will discuss with you.[\/vc_column_text][vc_row_inner limit_content=&#8221;&#8221;][vc_column_inner width=&#8221;1\/2&#8243;][vc_custom_heading heading_semantic=&#8221;h5&#8243; text_size=&#8221;h5&#8243; css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;194344&#8243; subheading=&#8221;At least 18 years of age&#8221;]Age[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h5&#8243; text_size=&#8221;h5&#8243; css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;183245&#8243; subheading=&#8221;Metastatic colorectal cancer&#8221;]Diagnosis[\/vc_custom_heading][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_custom_heading heading_semantic=&#8221;h5&#8243; text_size=&#8221;h5&#8243; css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;844161&#8243; subheading=&#8221;In general, 2 prior lines of therapy against colorectal cancer are needed&#8221;]Treatment history[\/vc_custom_heading][vc_custom_heading heading_semantic=&#8221;h5&#8243; text_size=&#8221;h5&#8243; css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;338816&#8243; subheading=&#8221;Independent and able to carry on normal daily activities&#8221;]Health status[\/vc_custom_heading][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;7&#8243; bottom_padding=&#8221;7&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; enable_top_divider=&#8221;default&#8221; top_divider=&#8221;gradient&#8221; shape_top_h_use_pixel=&#8221;&#8221; shape_top_height=&#8221;500&#8243; shape_top_color=&#8221;color-138253&#8243; shape_top_opacity=&#8221;70&#8243; shape_top_index=&#8221;0&#8243; enable_bottom_divider=&#8221;default&#8221; bottom_divider=&#8221;gradient&#8221; shape_bottom_h_use_pixel=&#8221;&#8221; shape_bottom_height=&#8221;500&#8243; shape_bottom_color=&#8221;color-138253&#8243; shape_bottom_opacity=&#8221;70&#8243; shape_bottom_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;157560&#8243; row_name=&#8221;study-schedule&#8221; shape_top_color_type=&#8221;uncode-palette&#8221; shape_bottom_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_percent=&#8221;95&#8243; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; sticky=&#8221;yes&#8221; width=&#8221;5\/12&#8243; uncode_shortcode_id=&#8221;202503&#8243;][vc_custom_heading css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;191580&#8243;]What happens during the study?[\/vc_custom_heading][vc_column_text css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;951429&#8243;]If you are interested in participating, the study doctor will explain the study in detail, answer your questions, and give you an Informed Consent Form to read. If you agree to join the study, you will sign the form. Then, you will start the Screening process to check your eligibility.[\/vc_column_text][vc_empty_space empty_h=&#8221;2&#8243;][\/vc_column][vc_column column_width_percent=&#8221;95&#8243; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; css_animation=&#8221;alpha-anim&#8221; width=&#8221;7\/12&#8243; uncode_shortcode_id=&#8221;697546&#8243;][vc_custom_heading heading_semantic=&#8221;h4&#8243; text_size=&#8221;h4&#8243; uncode_shortcode_id=&#8221;123236&#8243;]Screening Period[\/vc_custom_heading][vc_column_text uncode_shortcode_id=&#8221;334448&#8243;]You will have health checks and tests to see if you are eligible for the study. This will take no more than 28 days.[\/vc_column_text][vc_empty_space empty_h=&#8221;2&#8243;][vc_separator sep_color=&#8221;&#8221; uncode_shortcode_id=&#8221;195028&#8243;][vc_empty_space empty_h=&#8221;2&#8243;][vc_custom_heading heading_semantic=&#8221;h4&#8243; text_size=&#8221;h4&#8243; uncode_shortcode_id=&#8221;196434&#8243;]Study Treatment Period[\/vc_custom_heading][vc_column_text uncode_shortcode_id=&#8221;735155&#8243;]You have an equal chance of receiving 1 of 3 treatments: the investigational study medicine alone, the investigational study medicine combined with a standard of care anti-cancer medicine, or an approved standard of care combination anti-cancer regimen. You will receive your study treatment in cycles and visit the study clinic for checkups, tests, and scans.<\/p>\n<p>Study treatment will continue as long as it is safe and helpful for you and you agree to continue. You can choose to withdraw your consent and leave the study at any time for any reason. Other reasons for stopping may include cancer progression, intolerable side effects, or other medical reasons.[\/vc_column_text][vc_empty_space empty_h=&#8221;2&#8243;][vc_separator sep_color=&#8221;&#8221; uncode_shortcode_id=&#8221;112387&#8243;][vc_empty_space empty_h=&#8221;2&#8243;][vc_custom_heading heading_semantic=&#8221;h4&#8243; text_size=&#8221;h4&#8243; uncode_shortcode_id=&#8221;143191&#8243;]Follow-up Period[\/vc_custom_heading][vc_column_text uncode_shortcode_id=&#8221;881730&#8243;]There is a Safety Follow-up Visit 30 days after your last dose of study treatment, then phone calls about every 3 months.[\/vc_column_text][vc_empty_space empty_h=&#8221;3&#8243;][\/vc_column][\/vc_row][vc_row unlock_row_content=&#8221;yes&#8221; row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;5&#8243; top_padding=&#8221;7&#8243; bottom_padding=&#8221;7&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; inverted_device_order=&#8221;yes&#8221; uncode_shortcode_id=&#8221;187378&#8243; row_name=&#8221;health-checks&#8221;][vc_column column_width_percent=&#8221;95&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;362861&#8243;][vc_custom_heading text_weight=&#8221;500&#8243; css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;184138&#8243;]What health checks &amp; tests can I expect?[\/vc_custom_heading][vc_column_text css_animation=&#8221;alpha-anim&#8221; uncode_shortcode_id=&#8221;120408&#8243;]You will be monitored closely by the study doctor and staff. 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